日本ゼオライト学会　刊行物 Publication of Japan Zeolite Association

In order to establish the way of sustainable organic synthesis of natural product such as lactone, the reactions of alkenyl carboxylic acid derivatives, such as acids, esters, nitriles, and amides, encapsulated in zeolite have been examined. Solid NMR measurement for some precalucinated HY zeolites revealed that the Si/Al ratio affected the efficiency of lactone formation. The reactions of four type reactants showed the interesting temperature effect on the regioselectivity between the 5-membered and 6-membered cyclization. Semiempirical molecular orbital calculation by using PM5 has been applied to evaluate the reactivity of encapsulated system.